Chungnam National University. Graduate School of New Drug Discovery and Development.

교수진 소개

HOME교수 및 연구활동교수진 소개


교수실한국화학연구원, 의약화학연구센터, E1동 216호 (042-860-7163)
실험실천연물화학연구실 (042-860-7162)

학력 (Education)

학사: 1975~1979, 성균관대학교 약학과 
석사: 1979~1981, 서울대학교 약학과 생명약학전공 
박사: 1981~1988, 서울대학교 약학과 생명약학전공 약학박사



경력 (Professional Experience)
1988~1989: 일본 Suntory Institute for Bioorganic Research (Post Doc.)
1989~1990: 미국 Columbia University, Department of Chemistry (Post Doc.)
1990~현재한국화학연구원 신물질연구본부 책임연구원



주요 연구 활동

Isolation of bioactive components from natural resources
Phytochemical investigation of medicinal plants.
Chemical modification of bioactive compounds of natural origin
Natural product library


대표 논문 
Choi YH, Yoo DS, Cha MR, Choi CW, Kim YS, Choi SU, Lee KR, Ryu SY. Antiproliferative Effects of Saponins from the Roots of Platycodon grandiflorum on Cultured Human Tumor Cells. J Nat Prod. 73(11):1863-7 (2010)

Choi CW, Choi YH, Cha MR, Yoo DS, Kim YS, Yon GH, Hong KS, Kim YH, Ryu SY. Yeast α-glucosidase inhibition by isoflavones from plants of Leguminosae as an in vitro alternative to acarbose. J Agric Food Chem. 58(18):9988-93 (2010).

Choi CW, Choi YH, Cha MR, Yoo DS, Kim YS, Yon GH, Choi SU, Kim YH and Ryu SY. A New Glycoside of Resveratrol dimer From Stem bark of Vitisvinifera. Bull. Korean Chem. Soc. 31(11), 2442-2450 (2010).

Keon Wook Kang, Soo Jin Oh, Shi Yong Ryu, Gyu Yong Song, Bong-Hee Kim, Jong Seong Kang, Sang Kyum Kim, Evaluation of the total oxy-radical scavenging capacity of catechins isolated from green tea. Food Chemistry 121 (2010) 10891094.

Cha MR, Choi YH, Choi CW, Kim YS, Kim YK, Ryu SY, Kim YH, Choi SU. Galbanic Acid, a Cytotoxic Sesquiterpene from the Gum Resin of Ferula asafoetida, Blocks Protein Farnesyltransferase. Planta Med. 77, (2011).

Lee JH, Choi S, Lee Y, Lee HJ, Kim KH, Ahn KS, Bae H, Lee HJ, Lee EO, Ahn KS, Ryu SY, Lü J, Kim SH. Herbal Compound Farnesiferol C Exerts Antiangiogenic and Antitumor Activity and Targets Multiple Aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) Signaling Cascades. Mol Cancer Ther; 9(2), 389-399 (2010)

Moon MK, Ahn JY, Kim S, Ryu SY, Kim YS, Ha TY. Ethanol Extract and Saponin of Platycodon grandiflorum Ameliorate Scopolamine-Induced Amnesia in Mice. J Med Food. 13(3):584-8 (2010)


Kim MR, Cha MR, Choi YH, Choi CW, Choi SU, Kim YS, Kim YK, Kim YH, Ryu SY. Sesquiterpene Glycosides from the whole Plant Extract of Youngia japonica. Kor.J. Pharmacogn. 41(2),103 - 107(2010). 

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