Chungnam National University. Graduate School of New Drug Discovery and Development.

교수진 소개

HOME교수 및 연구활동교수진 소개

최성운

최성운교수
전공분야의약화학/drug design/방사능표지진단시약
교수실신약전문대학원 423호 (042-821-5294)
실험실신약전문대학원 425호 (042-821-7951)
이메일schoi@cnu.ac.kr
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학력 (Education)

학사경희대학교 약학대학 1985

석사경희대학교 약학대학 1990

박사: Northeastern Univ.(Boston) 1998

 

경력 (Professional Experience)

1988 ~ 1990 : 경희대학교 약학대학 실험조교

1988 ~ 1991 : 원자력병원 당직약사

1993 ~ 1998 : Northeastern Univ. 연구조교 RA

1998 ~ 2001 : Post-Doc Harvard Medical School/Mass. General Hospital/Radiology/Nuclear Medicine Scientist, Research Scientist

2001 ~ 2011 : Partners/Lab. for Drug Discovery in Neurodegeneration/Harvard Medical school Instructor

2009 ~ 2011 : Harvard Medical School/Neurology

2011 ~ 현재 부교수 충남대학교/과학수사학과

2014 ~ 현재 교수 충남대학교/신약개발학과

 

주요 연구 활동

1. Design of Organic Drug Candidates & Radiolabeling Agents

- Design and Synthesis of Drug Candidates & Precursors for Radiolabeling

- Cold Labeling

2. Drug(illicit drug) Analysis

- Organic Synthesis on TLC plates

- Design and Synthesis of color producing reagents

3. Fingerprint Analysis(Forensic Dept.)

-Development methodology for Latent Fingerprints

 

 

대표논문​

 

J Med Chem (2014) 57, 7900-7915

Structure-Activity Relationship of 3,5-Diaryl-2-aminopyridine ALK2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants

 

EMBO Mol Med (2013) 5, 116 (on line)

Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel druglike compounds

 

Bioorganic &Medicinal Chemistry Letters Sept. 2012, 22 (17) 56855688

Optimization of tricyclic Nec-3 necroptosis inhibitors for in vitro liver microsomal stability

 

Korean Journal of Scientific Criminal InvestigationMarch, 2011 5(1), 18

Inhibition of Melanin Synthesis by Pro-drug of Gentisyl Alcohol

 

Cancer CellOctober 19, 2010 (18), 382395

Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage 

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